Reformulation
of HIV treatment will save more children’s lives – UN 
5 June 2015
– The United States Food and Drug Administration (FDA) has approved a new
antiretroviral formulation that can be mixed with food, making it easier for
children living with HIV to take their life-saving medicines, the Joint UN
Programme on HIV/AID (UNAIDS) and the UN Children’s Fund (UNICEF) announced
today.
“Treatment
innovations such as this that replace unpleasant and bad tasting medicines are
a real breakthrough, accelerating access to treatment for children and keeping
our youngest healthy,” said Executive Director of UNAIDS, Michel Sidibé. “It is
unacceptable that only 24 per cent of children living with HIV have access to
antiretroviral medicines,” he added.
The
treatment is heat stable and more palatable than medicines currently available,
making it particularly suitable for treating very young children.
“This new
formulation is a step in the right direction towards saving more lives of
children living with HIV,” said Craig McClure, UNICEF’s Chief of HIV/AIDS
section. “We expect it to greatly improve treatment access for many more
children and support UNICEF’s equity focused programming aimed at reaching the
most disadvantaged children throughout the world.”
HIV
infection progresses rapidly in children and, in highly impacted countries, is
a major contributor to child morbidity and mortality. Without treatment, one in
three children who become infected with HIV will die before their first
birthday. Half will die before their second birthday.
Early
initiation of antiretroviral treatment in children substantially reduces the
risk of death. Many countries have not been able to fully implement this World
Health Organization (WHO) recommendation because of the challenge of not having
a more appropriate, heat stable and palatable paediatric formulation of
lopinavir/ritonavir used as part of the treatment options for children under 3
years of age.
Despite
global efforts to accelerate access to HIV paediatric care and treatment, fewer
than 800,000 of the 3.2 million children living with HIV worldwide had access
to antiretroviral medicines in 2013.
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